Dr Egene Braunwald

Father of Cardiology

Dr.Braunwald, M.D. is the Distinguished Hersey Professor of Medicine at Harvard Medical School, and the founding Chair of the TIMI Study Group at the Brigham and Women’s Hospital. Dr. Braunwald trained at New York University School of Medicine and served his Medical Residency at the Johns Hopkins Hospital. He served as Chief of Cardiology and as Clinical Director of the National Heart, Lung and Blood Institute, and founding Chair of Medicine at the University of California, San Diego. From 1972 to 1996 he was Chairman of the Department of Medicine at the Brigham and Women's Hospital. From 1980 to 1989 he also served as Chairman of the Department of Medicine at the Beth Israel Hospital and Blumgart Professor of Medicine atHarvard Medical School. He was a founding trustee and Chief Academic Officer of Partners HealthCare System.

Dr. Braunwald’s first major paper was published in Circulation Research in July 1954, and he has been a major force in cardiology since then. His early work focused on the control and assessment of ventricular function and he was the first to measure both left ventricular ejection fraction and left ventricular dp/dt in patients. His group showed the first neurohumoral defect inhuman heart failure, defined the pathophysiology of hypertrophic cardiomyopathy and demonstrated salvage of ischemic myocardium following coronary occlusion. For the past 32 years, he and his colleagues at the TIMI Study Group demonstrated improved outcomes with a patent coronary artery which led to the widely accepted “open artery hypotheses.” They were the first to show the benefit of preventing adverse remodelling of the infarcted ventricle with ACE inhibition. In the PROVE-IT TIMI 22 Trial, they demonstrated the benefit of more intensive reduction of LDL cholesterol in high risk coronary artery patients, which changed practice guidelines and favourably affected the lives of millions.

Dr. Braunwald was an editor of Harrison's Principles of Internal Medicine for 12 editions, and the founding editor of Heart Disease, now in its 11th Edition, the most influential textbooks in their fields. Science Watch listed Dr. Braunwald as the most frequently cited author in Cardiology; he has an h index of 208. He has received numerous honours and awards including the Distinguished Scientist and Lifetime Achievement Awards of the American College of Cardiology, Research Achievement, and Herrick Awards of the American Heart Association, and the Gold Medal of the European Society of Cardiology. He received an honorary Doctor of Science from the University of Oxford and is the recipient of honorary doctorates from twenty three other distinguished universities on three continents. The American College of Cardiology and the Heart Failure Association of the European Society of Cardiology have established annual lectures in his name. Harvard University established the Eugene Braunwald endowed Chair in Medicine. Dr. Braunwald was the first adult cardiologist elected to the National Academy of Sciences of the U.S. The living Nobel Prize winners in medicine voted Dr. Braunwald as “the person who has contributed the most to cardiology in recent years”.